After graduation he first worked in a local state department in Ningbo as an Engineer, and then he went to Guangzhou and worked for Sybase there. He founded NetEase and became the richest individual in Chinese mainland in the year of 2003 (7.6 billion yuan). According to the Hurun Report 2013, his net worth is estimated to be $5.2 billion.
In 2012, it was confirmed that Ding branched NetEase's activities out into pork production. The pig farm is centered around Technology and environmental sustainability, and is not meant to become a major arm of the company.
Ding made significant contributions to the development of computer networks in mainland China. In late 2016, Ding was looking into investing in the property sector, and travelled to Zimbabwe] in December, and to the United Kingdom. As of February 2018, Ding's fortune was estimated to be $18.3 billion, while in 2017, was ranked at #52 on Forbes's billionaires list.
In May 2017, venture capital firm Sinovation Ventures, US-based Meituan-Dianping, and Ali Baba competitor JD invested a total of US$23 million into the farm.