Georges J. F. Kohler

About Georges J. F. Kohler

Who is it?: Immunologist, Biologist
Birth Day: April 17, 1946
Birth Place: Munich, Germany, German
Died On: March 1, 1995(1995-03-01) (aged 48)\nFreiburg im Breisgau
Birth Sign: Taurus
Known for: monoclonal antibodies
Awards: Nobel Prize in Physiology or Medicine in 1984
Institutions: Max Planck Institute of Immunobiology
Doctoral advisor: Fritz Melchers

Georges J. F. Kohler Net Worth

Georges J. F. Kohler was bornon April 17, 1946 in Munich, Germany, German, is Immunologist, Biologist. Georges J. F. Kohler was a German immunologist and biologist who received Nobel Prize in Physiology or Medicine in 1984 for his role in the development of monoclonal antibodies. He shared the prize with Cesar Milstein, a renowned immunologist and biochemist. Kohler tasted success early on in his career. He was merely 28 when he was selected for a postdoctoral fellowship at the Laboratory of Molecular Biology in Cambridge, England. Kohler grabbed the opportunity and travelled to Cambridge in 1974. Same year, Kohler successfully invented a method of forcing immune system cells to make pure antibodies against a chosen antigen, instead of the profusion of different agents that usually greet an invading virus or bacterium. The discovery of the principle for production of monoclonal antibodies was revolutionary in the scientific world as it helped in the diagnosis of diseases and in carrying therapeutic agents to particular body tissues. Interestingly, though Kohler was the driving force behind the discovery, as he played a prominent role in conceiving and executing the experiment, he was written off by the scientific world who credited Milstein for the same. It was only in 1984 that his role in developing hybridomas was fully recognized and he was jointly awarded the Nobel Prize along with Cesar Milstein.
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💰 Net worth: Under Review

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Biography/Timeline

1974

In April 1974 Köhler took up a post-doctoral research fellowship at the Laboratory of Molecular Biology in Cambridge, UK where he began working with César Milstein to develop a laboratory tool that could help them investigate the mechanism that underlies the diversity of antibodies. It was during this work that they devised their hybridoma technique for the production of antibodies. Köhler continued his collaboration on the technique when he returned to Basel Institute of Immunology in April 1974. Köhler remained at the Basel Institute for another nine years, during which time he continued investigating antibody diversity and in the early 1980s began working on the development of transgenic mice as a tool to understand the mechanism that underlies self-tolerance. In 1986 Köhler became Director of the Max Planck Institute of Immunobiology where he worked until his death in 1995.

1984

Together with César Milstein and Niels Kaj Jerne, Köhler won the Nobel Prize in Physiology or Medicine in 1984, "for work on the immune system and the production of monoclonal antibodies". Milstein and Köhler's technique for producing monoclonal antibodies laid the foundation for the exploitation of antibodies for diagnostics and therapeutics and many scientific applications.