Albrecht Kossel

About Albrecht Kossel

Who is it?: Biochemist
Birth Day: September 16, 1853
Birth Place: Rostock, Germany, German
Died On: 5 July 1927(1927-07-05) (aged 73)\nHeidelberg, Germany
Birth Sign: Libra
Alma mater: University of Strassburg University of Rostock
Known for: Nucleic acids
Awards: 1910 Nobel Prize in Physiology or Medicine
Doctoral students: Edwin B. Hart

Albrecht Kossel Net Worth

Albrecht Kossel was bornon September 16, 1853 in Rostock, Germany, German, is Biochemist. Albrecht Kossel was a distinguished German biochemist and an avant-garde in the study of genetics. He was awarded the ‘Nobel Prize for Physiology or Medicine’ in 1910 for his contributions in analysing the chemical composition of one of the genetic substances of biological cells, the nucleic acids. Several techniques were applied by him and his students including hydrolysis to isolate and chemically determine the five organic compounds or nucleobases of nucleic acids as adenine, thymine, guanine, cytosine and uracil. These nucleobases are essential in the formation of the two nucleic acid types, DNA and RNA, the genetic substance present in living cells. He also extensively conducted research on composition of proteins and discovered the amino acid histidine, agmatine and thymic acid. He served as Professor of Physiology and later Director of the ‘Physiological Institute’ at the ‘University of Marburg’. He also became director of the ‘Heidelberg Institute for Protein Investigation’. He was a great influence for his students and also collaborated with some of them namely Henry Drysdale Dakin and Edwin B. Hart, all prominent researchers in biochemistry. He contributed and later edited the ‘Zeitschrift für Physiologische Chemie’, a publication founded by imminent German physiologist and chemist as also his professor cum mentor Felix Hoppe-Seyler.
Albrecht Kossel is a member of Scientists

💰 Net worth: Under Review

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Famous Quotes:

The processes of life are like a drama, and I am studying the actors, not the plot. There are many actors, and it is their characters which make this drama. I seek to understand their habits, their peculiarities.

— Albrecht Kossel, New York Times interview

Biography/Timeline

1869

After completing his university studies, Kossel returned to the University of Strassburg as research assistant to Felix Hoppe-Seyler. At the time, Hoppe-Seyler was intensely interested in research concerning an acidic substance that had first been chemically isolated from pus cells by one of his former students, Friedrich Miescher, in 1869. Unlike protein, the substance contained considerable amounts of phosphorus, but with its high acidity, it was unlike any cellular substance that had yet been observed.

1872

In 1872, Kossel attended the University of Strassburg to study Medicine. He studied under Felix Hoppe-Seyler, who was head of the department of biochemistry, the only such institution in Germany at the time. He attended lectures by Anton de Bary, Waldeyer, August Kundt, and Baeyer. He completed his studies at University of Rostock, and passed his German medical license exam in 1877.

1877

Kossel contributed to early issues of the Zeitschrift für Physiologische Chemie (Journal of Physiological Chemistry). This publication was founded by his professor and mentor, Felix Hoppe-Seyler, in 1877, the same year that Kossel started work as his research assistant. After Hoppe-Seyler's death in 1895, Kossel took over editorship of the Zeitschrift and continued in that role until his own death in 1927.

1883

In 1883, Kossel left Strassburg to become Director of the Chemistry Division of the Physiological Institute at the University of Berlin. In this post, he succeeded Eugen Baumann and worked under the supervision of Emil du Bois-Reymond.

1885

Kossel continued his previous work on the nucleic acids. During the period 1885 to 1901, he was able to isolate and name its five constituent organic compounds: adenine, cytosine, guanine, thymine, and uracil. These compounds are now known collectively as nucleobases, and they provide the molecular structure necessary in the formation of stable DNA and RNA molecules.

1886

In 1886, Kossel married Luise Holtzman, daughter of Adolf Holtzmann. Holtzmann was Professor at the University of Heidelberg, lecturing in German literature as well as Sanskrit. He was also a noted philologist of his day. The couple had three children, two of whom survived to maturity: Walther, born in 1888, and daughter Gertrude, born in 1889.

1888

Son Walther Kossel (1888–1956) became a prominent Physicist and was professor of theoretical physics and Director of the Physics Institute at the University of Tübingen. He is known for his theory of the chemical bond (ionic bond/octet rule), the Sommerfeld–Kossel displacement law, and other achievements.

1895

In 1895, Kossel was professor of physiology as well as Director of the Physiological Institute at the University of Marburg. Around this time, he began investigations into the chemical composition of proteins, the alterations in proteins during transformation into peptone, the peptide components of cells, and other investigations.

1896

In 1896, Kossel discovered histidine, then worked out the classical method for the quantitative separation of the "hexone bases" (the alpha-amino acids arginine, histidine, and lysine). He was also the first to isolate Theophylline, a therapeutic drug found naturally in tea and cocoa beans.

1901

In 1901, Kossel was named to a similar post at Heidelberg University, and became Director of the Heidelberg Institute for Protein Investigation. His research predicted the discovery of the polypeptide nature of the protein molecule.

1907

Another of Kossel's students was American biochemist Edwin B. Hart, who would later return to the United States to participate in the "Single-grain experiment" (1907–1911) and be part of research teams that would determine the nutritive causes of anemia and goiter. Another was Otto Folin, an American Chemist who discovered Phosphocreatine.

1910

Kossel was awarded the Nobel Prize in Physiology or Medicine in 1910 for his research in cell biology, the chemical composition of the cell nucleus, and for his work in isolating and describing nucleic acids. The award was presented on 10 December 1910.

1911

In the autumn of 1911, Kossel was invited to the United States to deliver the Herter Lecture at Johns Hopkins. Traveling with his wife Luise and daughter Gertrude, he took the opportunity to travel and to visit acquaintances, one of which was Eugene W. Hilgard, professor emeritus of agricultural chemistry at the University of California at Berkeley, who was also his wife's cousin. He also visited and delivered lectures at several other universities, including the University of Chicago.

1923

In 1923, Kossel was honored by being named Germany's representative to the Eleventh Physiological Congress in Edinburgh, Scotland. When he appeared before the assembled Scientists, they gave him an ovation that lasted several minutes. At the congress, he was conferred an honorary degree by the University of Edinburgh.

1924

In 1924, Kossel became professor emeritus, but continued to lecture at Heidelberg University. In April, 1927, he attended the Lister Centenary Celebration held in England.

1927

Luise Kossel died in 1913 of acute pancreatitis. Kossel died quietly on 5 July 1927, after a recurring attack of angina pectoris. He is buried in Heidelberg, Germany.

1953

Albrecht Kossel is considered one of the great Scientists of biochemistry and genetics. By isolating and defining nucleic acid and the nucleobases, he provided the necessary precursors that led to the double-helix model of DNA, devised by James D. Watson and Francis Crick in 1953.