Michael S. Brown

About Michael S. Brown

Who is it?: Geneticist
Birth Day: April 13, 1941
Birth Place: Brooklyn, New York, United States, United States
Birth Sign: Taurus
Alma mater: University of Pennsylvania University of Pennsylvania School of Medicine
Known for: Regulation of cholesterol metabolism
Spouse(s): Alice Lapin (m. 1964)
Children: two
Awards: Heinrich Wieland Prize (1974) Richard Lounsbery Award (1979) William Allan Award (1985) Nobel Prize in Physiology or Medicine (1985) National Medal of Science (1988) ForMemRS (1991)
Fields: Biology
Website: profiles.utsouthwestern.edu/profile/10894/michael-brown.html

Michael S. Brown Net Worth

Michael S. Brown was bornon April 13, 1941 in Brooklyn, New York, United States, United States, is Geneticist. Michael S. Brown is an American geneticist who won a share of the Nobel Prize in Physiology or Medicine in 1985. Best known for his work on the metabolism of cholesterol in the human body, he worked in collaboration with Joseph L. Goldstein to research on cholesterol metabolism and discovered that human cells have low-density lipoprotein (LDL) receptors that extract cholesterol from the bloodstream. The duo then worked together to develop new drugs with cholesterol-lowering compounds which is today used by millions of people around the world. The son of a salesman, he graduated from the College of Arts and Sciences of the University of Pennsylvania before earning his MD from the University Of Pennsylvania School Of Medicine. After getting his degree he spent the next two years as intern and resident in Internal Medicine at the Massachusetts General Hospital in Boston. This is where he met Joseph L. Goldstein, a fellow intern, with who he formed a long term personal friendship and professional collaboration. Brown and Goldstein began their research on cholesterol metabolism in humans and over the years made many significant discoveries in the field and also developed new drugs to manage cholesterol. In recognition of their work, the duo was honored with the Nobel Prize in Physiology or Medicine in 1985.
Michael S. Brown is a member of Scientists

💰 Net worth: $1.9 Million

Some Michael S. Brown images

Awards and nominations:

Brown has won numerous awards and honors including:

Biography/Timeline

1962

Brown was born in Brooklyn, New York, the son of Evelyn, a homemaker, and Harvey Brown, a textile salesman. Graduated from Cheltenham High School (Wyncote, PA). Brown graduated from the University of Pennsylvania in 1962 and received his M.D. from the University of Pennsylvania School of Medicine in 1966.

1984

Their findings led to the development of statin drugs, the cholesterol-lowering compounds that today are used by 16 million Americans and are the most widely prescribed medications in the United States. Their discoveries are improving more lives every year, both in the United States and around the world[needs citation]. New federal cholesterol guidelines will triple the number of Americans taking statin drugs to lower their cholesterol, reducing the risk of heart disease and stroke for countless people. Following these important advances, their team of dedicated researchers elucidated the role of lipid modification of proteins (protein prenylation) in cancer. In 1984 he was awarded the Louisa Gross Horwitz Prize from Columbia University together with Joseph L. Goldstein (Co-recipient of 1985 Nobel Prize in Physiology or Medicine). In 1988, Brown received National Medal of Science for his contributions to the world of Medicine.

1993

In 1993, their trainees Xiaodong Wang and Michael Briggs purified the Sterol regulatory element binding proteins (SREBPs). Since 1993, Drs. Brown, Goldstein, and their colleagues have described the unexpectedly complex machinery by which cells maintain the necessary levels of fats and cholesterol in the face of varying environmental circumstances. Dr. Brown holds The W. A. (Monty) Moncrief Distinguished Chair in Cholesterol and Arteriosclerosis Research; is a Regental Professor of the University of Texas; holds the Paul J. Thomas Chair in Medicine; and is a member of the Board of Scientific Directors at The Scripps Research Institute. Frequently mentioned as a candidate for nationally-prominent positions in scientific administration, Dr. Brown, like his colleague Joseph L. Goldstein, elects to continue hands-on involvement with research, leading a research team that typically includes a dozen doctoral and postdoctoral trainees. He and his colleague are among the most highly cited Scientists in the world.

2007

Brown is also on the prestigious Prix Galien USA Committee that "recognizes the technical, scientific and clinical research skills necessary to develop innovative medicines". The inauguration of the Prix Galien in the US, the equivalent of the Nobel Prize in this field, was in September 2007, and the winners were selected by a preeminent scientific and learned committee that included 7 Nobel laureates, of which Brown was one.