She became interested in acting at the age of 10, after her brother introduced her to Pulp Fiction. She began her career in 2002 with brief appearances in the TV series Jeremiah and John Doe. From 2007 to 2009, she played the role of Andy Jensen on Kyle XY. In 2008 she starred in the Hallmark Channel original movie Every Second Counts.
In 2009, Apanowicz was cast as Lacy Rand, a series regular, in the television drama Caprica with Eric Stoltz and Alessandra Torresani. She later appeared in Hellcats. In 2012, she guest starred in the second season of Jane Espenson's romantic comedy web series, Husbands.
In 2013, Apanowicz appeared as Emily in the series Continuum. She also appeared in the Eli Roth horror film The Green Inferno as Samantha. Although it was filmed in 2012, The Green Inferno was internationally released in 2015.
In 2017, Apanowicz was cast as Angela in the action film Volition. The film is set to be released somewhere in 2018.