Famous as the co-founder of People for the Ethical Treatment of Animals (PETA), Newkirk was instrumental in securing a 1985 amendment to the United States' Animal Welfare Act.
She joined the animal rights movement in the early 1970s and helped bring about legislation that set up a public fund for veterinary care and established Washington D.C.'s first clinic for the spaying and neutering of pets. A decade later, she and fellow Activist Alex Pacheco founded PETA.
Her animal rights-themed publications include The PETA Practical Guide to Animal Rights (published in 2009) and Making Kind Choices (2005).
She and Sea Shepherd Conservation Society founder Paul Watson both had high-profile careers as animal rights Activists.