Gerald Edelman

About Gerald Edelman

Who is it?: Immunologist
Birth Day: July 01, 1929
Birth Place: Ozone Park, New York City, New York, United States, United States
Died On: May 17, 2014(2014-05-17) (aged 84)\nLa Jolla, California
Birth Sign: Leo
Alma mater: Ursinus College, University of Pennsylvania School of Medicine, The Rockefeller University
Spouse(s): Maxine M. Morrison (m. 1950; 3 children)
Awards: Nobel Prize in Physiology or Medicine in 1972
Fields: Immunology Neuroscience Philosophy of Mind

Gerald Edelman Net Worth

Gerald Edelman was bornon July 01, 1929 in Ozone Park, New York City, New York, United States, United States, is Immunologist. Gerald Edelman was a noted American Immunologist who, along with Rodney Robert Porter, won the 1972 Nobel Prize in Physiology or Medicine. The duo won the Nobel Prize for their discovery of the structure of antibody molecules. Initially, Edelman wanted to be a concert vocalist; but later made up his mind to become a doctor. However, while working in U.S. Army Medical Corp in Paris he read a book about immunology, which sparked an interest in antibodies in him. So, he went back to America to join Rockefeller institute for his Ph.D. degree. He then worked on antibodies, which he found were made up of chains of amino acids held together by disulfide bonds. He made exact replica of an antibody and explained how the body produces them in response to antigens. The work not only earned him the Nobel Prize, but also opened the door for further investigations. Later, he started working on primary cellular process and discovered cell adhesion molecules, which binds cells together to form tissues. He then began to work on how the brain gives rise to the mind and established the theory of Neuronal Group Selection, also known as ‘Neural Darwinism’. He also authored number of books, in some of which he had also explained his ideas to layman.
Gerald Edelman is a member of Scientists

💰 Net worth: $18 Million

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Famous Quotes:

The impact of Edelman's and Porter's discoveries is explained by the fact that they provided a clear picture of the structure and mode of action of a group of biologically particularly important substances. By this they laid a firm foundation for truly rational research, something that was previously largely lacking in immunology. Their discoveries represent clearly a break-through that immediately incited a fervent research activity the whole world over, in all fields of immunological science, yielding results of practical value for clinical diagnostics and therapy.

Biography/Timeline

1929

Gerald Edelman was born in 1929 in Ozone Park, Queens, New York, to Jewish parents, physician Edward Edelman, and Anna (née Freedman) Edelman, who worked in the insurance industry. He studied violin for years, but eventually realized that he did not have the inner drive needed to pursue a career as a concert Violinist, and decided to go into medical research instead. He attended public schools in New York, graduating from John Adams High School, and going on to college in Pennsylvania where he graduated magna cum laude with a B.S. from Ursinus College in 1950 and received an M.D. from the University of Pennsylvania School of Medicine in 1954.

1950

Edelman married Maxine M. Morrison in 1950. They have two sons, Eric, a visual Artist in New York City, and David, an adjunct professor of neuroscience at University of San Diego. Their daughter, Judith Edelman, is a bluegrass musician, recording Artist, and Writer. Some observers have noted that a character in Richard Powers' The Echo Maker may be a nod at Edelman.

1957

After a year at the Johnson Foundation for Medical Physics, Edelman became a resident at the Massachusetts General Hospital; he then practiced Medicine in France while serving with US Army Medical Corps. In 1957, Edelman joined the Rockefeller Institute for Medical Research as a graduate fellow, working in the laboratory of Henry Kunkel and receiving a Ph.D. in 1960. The institute made him the Assistant (later Associate) Dean of Graduate Studies; he became a professor at the school in 1966. In 1992, he moved to California and became a professor of neurobiology at The Scripps Research Institute.

1960

While in Paris serving in the Army, Edelman read a book that sparked his interest in antibodies. He decided that, since the book said so little about antibodies, he would investigate them further upon returning to the United States, which led him to study physical chemistry for his 1960 Ph.D. Research by Edelman and his colleagues and Rodney Robert Porter in the early 1960s produced fundamental breakthroughs in the understanding of the antibody's chemical structure, opening a door for further study. For this work, Edelman and Porter shared the Nobel Prize in Physiology or Medicine in 1972.

1969

Edelman and his colleagues used cyanogen bromide and proteases to fragment the antibody protein subunits into smaller pieces that could be analyzed for determination of their amino acid sequence. At the time when the first complete antibody sequence was determined (1969) it was the largest complete protein sequence that had ever been determined. The availability of amino acid sequences of antibody proteins allowed recognition of the fact that the body can produce many different antibody proteins with similar antibody constant regions and divergent antibody variable regions.

1972

In its Nobel Prize press release in 1972, the Karolinska Institutet lauded Edelman and Porter's work as a major breakthrough:

1978

The first of Edelman's technical books, The Mindful Brain (1978), develops his theory of Neural Darwinism, which is built around the idea of plasticity in the neural network in response to the environment. The second book, Topobiology (1988), proposes a theory of how the original neuronal network of a newborn's brain is established during development of the embryo. The Remembered Present (1990) contains an extended exposition of his theory of consciousness.

1988

Topobiology is Edelman's theory which asserts that morphogenesis is driven by differential adhesive interactions among heterogeneous cell populations and it explains how a single cell can give rise to a complex multi-cellular organism. As proposed by Edelman in 1988, topobiology is the process that sculpts and maintains differentiated tissues and is acquired by the energetically favored segregation of cells through heterologous cellular interactions.

1992

In his later career, Edelman was noted for his theory of consciousness, documented in a trilogy of technical books and in several subsequent books written for a general audience, including Bright Air, Brilliant Fire (1992), A Universe of Consciousness (2001, with Giulio Tononi), Wider than the Sky (2004) and Second Nature: Brain Science and Human Knowledge (2007).

1993

Edelman founded and directed The Neurosciences Institute, a nonprofit research center in San Diego that between 1993 and 2012 studied the biological bases of higher brain function in humans. He served on the scientific board of the World Knowledge Dialogue project.

2014

Later in his life, he had prostate cancer and Parkinson's disease. Edelman died on May 17, 2014 in La Jolla, California, aged 84.