Fred DeLuca was born in Brooklyn, New York, on October 3, 1947 to Italian American parents Carmela and Salvatore DeLuca. At the age of 10, DeLuca moved to Amsterdam, New York, where he and his family became friends with Peter Buck. Once in his teens, he moved with his family to Bridgeport, Connecticut. After succeeding in his Business, DeLuca realized his dream to go to college and graduated from the University of Bridgeport.
The first shop opened on August 28, 1965 at a mediocre location in the city of Bridgeport, Connecticut. The first year of Business was a learning experience and a challenge. A year later they opened their second location, having realized that visibility and marketing were key factors to success. DeLuca believed that the biggest mistake he made was where he set up his very first shop as it was a "crummy location." The third outlet was in a highly visible location and that location is still there today.
In 1978, Subway's 100th store opened, and reached the 1,000 store mark in 1987. Explosive growth continued with Subway opening 1,100 units in 1993 alone. By comparison, McDonald's opened 800 that same year.
At the graduation commencement in 2002, DeLuca received an honorary Doctor of Humane Letters (L.H.D.) from his alma mater, the University of Bridgeport.
On July 15, 2013, DeLuca announced that he was being treated for leukemia. DeLuca died on September 14, 2015, at Lauderdale Lakes, Florida.