Best known as the voice of "Three-Dog" in the science-fiction video game Fallout 3, he also appeared in episodes of such television series as The Wire and Homicide: Life on the Street.
Following his 1986 graduation from Brown University, he lived in New York City, Los Angeles, and Washington, D.C.
He and his family were the inspiration for a Disney Channel Movie called The Color of Friendship; the film told the true story of the Dellums' Apartheid-era housing of a South African exchange student.
The son of Democratic politician, Oakland Mayor, and United States Representative Ron Dellums, he grew up in central California and Washington, D.C. His mother, Leola Roscoe, had a career as an attorney; his sister, Piper Dellums, became a non-fiction writer.
In his twenties, he appeared in such Spike Lee films as Do the Right Thing and She's Gotta Have It.