Mankiewicz began his career as a reporter and an anchor for WCSC-TV (a CBS affiliate) in Charleston, South Carolina. He joined WAMI in Miami, Florida in 1998, where he served as anchor of The Times, a daily news magazine show and the station’s highlight program.
Mankiewicz is currently a host of Turner Classic Movies. When he made his debut on TCM in September 2003, he became the second host hired in the network’s history (Robert Osborne being the first). As a film critic, Mankiewicz co-hosted the nationally syndicated television series At the Movies from 2008 to 2009 and currently co-hosts the on-line film review show What the Flick?! on The Young Turks Network.
Mankiewicz has made cameo appearances in the Lifetime television movie The Bling Ring (2011) and the action film White House Down (2013). Mankiewicz also appears regularly on other shows as a political and media commentator, including The Michael Brooks Show in 2017.